Commonly labeled as an anti-estrogen, Tamoxifen Citrate functions as both an antagonist and an agonist. This indicates that it inhibits estrogen effects in certain parts of the body while promoting estrogen-like effects in others.
This medication is frequently utilized by anabolic steroid users, despite not being a steroid itself. It can help mitigate estrogen-related side effects that may result from specific steroids. However, it is primarily used during Post Cycle Therapy (PCT).
Effects of Tamoxifen
For users of anabolic steroids, the benefits of Tamoxifen Citrate can be observed both during and after steroid use, with a focus on its use post-cycle. Although Tamoxifen Citrate does not reduce serum estrogen levels, it competes with estrogen for binding to receptors in breast tissue, preventing estrogen from exerting its effects. It may not significantly address water retention, and for some men, it may not provide sufficient protection against gynecomastia. The effectiveness varies based on individual estrogen levels and genetic factors. For additional protection, Aromatase Inhibitors (AIs) are recommended.
Tamoxifen Citrate also has testosterone-stimulating properties, which is crucial for anabolic steroid users. Steroid use naturally suppresses testosterone production, necessitating exogenous testosterone in cycles to counter negative feedback and avoid low testosterone levels. Post-cycle, Tamoxifen can expedite the recovery of testosterone production, enhancing efficiency.
In the context of treating breast cancer, the effects of Tamoxifen Citrate are notably clear. Estrogen promotes tumor growth; however, Tamoxifen Citrate blocks estrogen from binding to its receptors, effectively starving the cancer. This straightforward yet potent method is part of a treatment regimen that may begin with an AI before transitioning to a Selective Estrogen Receptor Modulator (SERM) like Tamoxifen. It is sometimes applied as a preventive measure for individuals with a strong familial history of breast cancer.
Side effects:Headaches, gastrointestinal distress, hot flashes, vaginal itching, bleeding, discharge or discomfort, rash, reduced white blood cell count, endometrial changes, elevated triglyceride levels, pulmonary embolism.How to use:
For breast cancer treatment, there are six protocols involving Tamoxifen Citrate, applicable to both male and female patients. Typically, doses range from 10-20mg taken twice daily. A standard initial dose is often 40mg per day (20mg twice daily). Many breast cancer patients may continue with 10-20mg daily to avert recurrence once remission is achieved.In contrast, for anabolic steroid users looking to prevent gynecomastia during their cycles, the usual dosage is also 10-20mg per day. If this range is ineffective, higher doses are not likely to help, and AIs should be considered.
Regarding Post Cycle Therapy (PCT), most plans commence with Tamoxifen Citrate at 40mg daily for 2-3 weeks, followed by a reduction to 20mg per day for another 2-3 weeks. For comprehensive PCT, it is common to include another SERM, Clomiphene Citrate (Clomid). For a complete guide on PCT, refer to the resource titled "How to Come off Steroids."
