- Active substance: Anastrozole
- Manufacturer: Sun Pharma
- Unit: 5tabs (1.00mg/tab) AnabrezActive ingredient: AnastrozoleAlternative names: Arimidex, Anastrozol, Anastrox, Anazole, Aremed.Active half-life 2 days
Anastrozole is a highly effective anti-estrogen that falls under the Aromatase Inhibitor (AI) category. Arimidex has demonstrated superior efficacy in treating breast cancer compared to conventional Nolvadex (Tamoxifen Citrate) and is favored by many anabolic steroid users for its ability to guard against estrogen-related complications during cycles. Numerous anabolic steroid users depend on Arimidex for estrogenic protection while using testosterone-based substances.
Effects of AnastrozoleAs an anti-estrogen, Arimidex is crucial for breast cancer patients, as many breast cancer types thrive on estrogen. While this may be a simplification, administering Arimidex effectively restricts the cancer's growth. Recently, Arimidex has emerged as the preferred anti-estrogen for treating hormone receptor-positive breast cancer, particularly in postmenopausal women.
For anabolic steroid users, the protective effects of Arimidex against estrogenic side effects are highly valued. Many anabolic steroids can produce estrogen-related symptoms due to the interaction of testosterone with the aromatase enzyme, which leads to increased estrogen levels, causing issues like gynecomastia and excessive water retention. Severe water retention has the potential to elevate blood pressure. Not all anabolic steroids aromatize, so not all can result in estrogen-linked side effects.
Incorporating Arimidex into a steroid cycle that includes aromatizing steroids can help guard against gynecomastia and water retention, also offering protection against hypertension. AI’s like Arimidex are undoubtedly the most potent anti-estrogens for mitigating estrogenic side effects. While SERM’s such as Nolvadex can also be effective, they are generally considered less potent and should be prioritized when feasible. It's worth noting that Arimidex can adversely impact cholesterol levels, as we will explore in the side effects section. However, it is possible to avoid cholesterol-related issues.
As a testosterone-enhancing agent, Arimidex can be advantageous in low testosterone treatment regimens and in Post Cycle Therapy (PCT) for anabolic steroid users. In situations of low testosterone, it is often inadequate on its own. Nevertheless, it can still be beneficial when used alongside exogenous testosterone therapy to mitigate estrogenic side effects. Some may attempt to use it during PCT, leading to positive outcomes, but it is not widely advised. The primary goal of a PCT protocol is to promote natural testosterone production to preserve lean muscle mass, manage body fat, and maintain overall health. Ultimately, the aim is normalization, which is unattainable when using Arimidex post-cycle due to drastic estrogen suppression. While elevated estrogen levels can be problematic, a certain amount is essential for proper body functioning, particularly for the immune system and cardiovascular health. Therefore, anabolic steroid users should reserve AI’s for active cycles and employ SERM’s during PCT.
Possible side effects:Headaches, nausea, hot flashes, high blood pressure, joint pain, depression, reduced bone mineral density, adverse effects on cholesterol levels,Administration guidelines:In breast cancer treatment, Arimidex is typically prescribed at a daily dosage of 1mg until there is a significant reduction in the cancer. Continued use may follow this stage, often transitioning to Nolvadex for preventive purposes once the cancer enters remission.
For anabolic steroid users, doses of Arimidex can vary, but 0.5-1mg every other day is the most common regimen. Few individuals require more than 1mg every other day, and many can effectively manage with half that dose. In therapeutic applications, such as treating low testosterone, even smaller doses may suffice. However, one exception exists for competitive bodybuilders, who may benefit from taking a full 1mg daily in the final 10-14 days before a competition. This can significantly enhance muscle definition, though it may lead to exhaustion. At this stage, many athletes are already operating on low energy levels due to their strict competition diet.