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Often classified as an anti-estrogen, Tamoxifen Citrate acts as both an antagonist and agonist. This indicates that it functions as an anti-estrogen in some regions of the body while exhibiting estrogenic effects in others.

This medication is utilized by many anabolic steroid users, although it is not a steroid itself. Users may turn to this drug during steroid cycles to mitigate estrogen-related side effects induced by certain steroids. Its primary use, however, is during Post Cycle Therapy (PCT).

For users of anabolic steroids, the benefits of Tamoxifen Citrate can be observed during and especially after anabolic steroid use. While Tamoxifen Citrate does not reduce serum estrogen levels, it does compete for receptors in breast tissue, thereby limiting estrogen binding. It's important to note that it may not effectively manage water retention and may not provide sufficient protection against gynecomastia for all individuals. The level of protection can depend on estrogen levels and individual genetics, so in cases requiring stronger measures, Aromatase Inhibitors (AIs) are advisable.

Tamoxifen Citrate also has testosterone-stimulating properties, which is critical for anabolic steroid users. Anabolic steroids can suppress natural testosterone production, necessitating the use of exogenous testosterone during steroid cycles to prevent low testosterone levels. Post-steroid cycle, Tamoxifen can facilitate and enhance the recovery of natural testosterone production.

For breast cancer patients, the effects of Tamoxifen Citrate are rather straightforward. Estrogen promotes the growth of cancer cells, and Tamoxifen Citrate blocks estrogen from attaching to these cells, effectively starving them. This treatment approach is generally combined with other therapies, often starting with an AI before transitioning to a Selective Estrogen Receptor Modulator (SERM) like Tamoxifen. It can also be utilized as a preventive measure for individuals with a strong familial history of breast cancer.

In the context of treating breast cancer, there are six different Tamoxifen Citrate treatment plans for both male and female patients. In these plans, typical dosages range from 10-20 mg taken twice daily, with a full dose of 40 mg per day being common at the outset of treatment. Many breast cancer patients may continue taking 10-20 mg per day indefinitely once in remission to help prevent recurrence. For anabolic steroid users, the standard dosage for gynecomastia prevention during a cycle is also 10-20 mg per day. If this dosage is ineffective, it is unlikely that higher doses will help, and consideration should be given to using AIs instead.

Finally, regarding PCT, most protocols start with Tamoxifen Citrate at doses of 40 mg per day for the first 2-3 weeks, followed by a decrease to 20 mg per day for another 2-3 weeks. Effective PCT often includes another SERM, Clomiphene Citrate (Clomid). For a complete overview of PCT, refer to "How to Come off Steroids."