In recent years, Finasteride has become popular among some users of anabolic steroids as a means to counteract androgenic side effects. These side effects vary significantly depending on genetics; notable is that certain men can use high dosages of steroids, which are typically androgenic, without experiencing related adverse effects. Genetics plays a crucial role in how androgenic effects manifest and in the body's response to and metabolism of the androgen dihydrotestosterone (DHT).
Effects of Finasteride:
The primary effect of Finasteride is to inhibit the conversion of testosterone to dihydrotestosterone, a process that occurs via the 5-alpha reductase enzyme. By blocking DHT, Finasteride helps prevent hair loss, as DHT can damage hair follicles. In addition, elevated DHT levels can cause prostate enlargement, which is a more serious concern than hair loss. Research has indicated that just six months of Finasteride treatment can significantly reduce or even completely reverse prostate enlargement.
When analyzing the effects of Finasteride, it is essential to consider its impact on users of anabolic steroids. Many anabolic steroids are DHT-derived, such as Oxymetholone (Anadrol), Methenolone (Primobolan), and Stanozolol (Winstrol); since there is no substrate for the 5-alpha reductase enzyme in these cases, Finasteride has no effect. However, in the case of testosterone-derived anabolic steroids, Finasteride's effects can be beneficial, particularly with Testosterone (in any form), Methyltestosterone (Metandren), and Fluoxymesterone (Halotestin).
When testosterone levels are elevated, there is more hormone available for the 5-alpha reductase enzyme to metabolize, potentially leading to increased DHT accumulation. This can heighten androgenic effects, which Finasteride may mitigate, helping to protect against hair loss and prostate enlargement. It is important to note that protection against hair loss is only relevant for those with a genetic predisposition to male pattern baldness; if a person is not predisposed, hair loss will not occur. However, for those who are predisposed, DHT can accelerate the hair loss process. Additionally, the use of Finasteride may help alleviate acne that can arise from a strong androgenic environment, but again, this depends on individual genetic sensitivity to acne.
Finasteride can help diminish the relative androgenic effects of the aforementioned anabolic steroids, including Testosterone, Methyltestosterone, and Fluoxymesterone. While Finasteride won't entirely eliminate the androgenicity of these hormones, it can significantly lessen it. If you are highly sensitive to androgenic side effects, it might be wise to steer clear of potent androgenic steroids. Males will still require exogenous testosterone while using anabolic steroids, but it is recommended to maintain it at a low level.
It’s worth noting that Finasteride may actually increase the androgenicity of certain steroids, particularly Nandrolone and its derivatives like Trenbolone. Therefore, it is advisable to avoid Finasteride when using these specific steroids. Furthermore, Finasteride does not impact DHT-derived steroids since there is nothing for the enzyme to metabolize, rendering it ineffective. If DHT-based steroids or highly androgenic steroids like Trenbolone are problematic for you, consider avoiding such substances.
Side effects:
Possible side effects include reduced libido and ejaculatory issues. Pregnant women or those who may become pregnant must not come into contact with this substance, as it can cause serious harm to the developing fetus.
How to use:
To address hair loss, the typical dose of Finasteride is 1mg daily, while doses up to 5mg daily may be necessary for treating prostate enlargement. For managing androgenic side effects related to specific anabolic steroid use, a dose of 1mg per day during steroid cycles is recommended.