Tamoxifen Citrate is commonly known as an anti-estrogen; however, it functions both as an antagonist and agonist. This means it can inhibit estrogen in some areas of the body while mimicking it in others.
Although many anabolic steroid users take this medication, it is not classified as a steroid. Users often turn to it during steroid cycles to alleviate estrogen-related side effects associated with certain steroids. However, its primary usage occurs during Post Cycle Therapy (PCT).
Effects of Tamoxifen
For anabolic steroid users, the beneficial effects of Tamoxifen Citrate can be observed both during and after steroid use, with the latter being more significant. While it does not decrease serum estrogen levels, it effectively binds to receptors in the breast area, blocking estrogen attachment. However, it may not greatly alleviate water retention issues, and its effectiveness in preventing gynecomastia can vary depending on individual estrogen levels and genetics. For those needing stronger protection, Aromatase Inhibitors (AIs) are suggested.
Another notable benefit of Tamoxifen Citrate is its ability to stimulate testosterone production. This is particularly crucial for anabolic steroid users, as anabolic steroids suppress natural testosterone production regardless of the type of steroid used. Consequently, most steroid cycles incorporate exogenous testosterone to prevent a drop in testosterone levels due to negative feedback. Post-steroid use, a means to reactivate testosterone production is essential. While this naturally occurs, it can be slow, and Tamoxifen may expedite and enhance efficiency.
For breast cancer patients, the effects of Tamoxifen Citrate are generally clearer than for anabolic steroid users. Since estrogen promotes cancer growth, Tamoxifen Citrate works by preventing estrogen from binding, effectively starving the cancer. This straightforward yet powerful treatment approach is often complemented with an AI initially, followed by a switch to a SERM like Tamoxifen Citrate. It may also be employed as a preventive measure for individuals with a strong family history of breast cancer.
Side effects:Common side effects include headaches, gastrointestinal disturbances, hot flashes, vaginal itching, bleeding, discharge or pain, rashes, lowered white blood cell count, changes in the endometrium, elevated triglyceride levels, and risk of pulmonary embolism.How to use:
For breast cancer treatment, there are six Tamoxifen Citrate protocols applicable to both males and females. Typically, dosages range from 10-20mg taken twice daily. A common initial dosage is 40mg per day (20mg taken twice daily). Many breast cancer patients may also opt to continue with a lower dose of 10-20mg per day indefinitely to prevent recurrence after remission.For anabolic steroid users aiming to prevent gynecomastia during cycles, a daily dosage within the range of 10-20mg is recommended. If this dosage falls short in effectiveness, a switch to AIs should be considered.
During Post Cycle Therapy (PCT), most plans start with Tamoxifen Citrate at 40mg daily for 2-3 weeks, followed by a reduction to 20mg daily for another 2-3 weeks. A complete PCT regimen may also include another SERM, Clomiphene Citrate (Clomid). For a comprehensive guide on PCT, refer to How to Come off Steroids.